Thursday, March 11, 2010

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Pravachol

Name              Trade Name Pravachol

                        Generic Name: Pravastatin 

 

Purpose         

To decrease total cholesterol, LDL, and triglycerides, and to raise HDL.

 

 

Action            

Pravachol inhibits an enzyme necessary to produce cholesterol in the liver.  It also facilitates the removal of LDL cholesterol from the blood.

 

 

Dose               

The dosing range is 10-80 mg at bedtime.  The Doctor wants you to start at _______mg.  Lower doses are used in patients with significant kidney or liver problems.

 

 

You should not take Pravachol if any of the following apply:

 

 

 

  • You have active liver disease or unexplained elevated liver enzymes.

     

  • Females who are pregnant, nursing, or likely to conceive.

     

  • You take Erythromycin type antibiotics (Ery-Tab, E-mycin, Biaxin).

     

·  You should be cautious about taking Pravachol with Lopid (Gemfibrozil), Tricor, or high doses of Niacin (Niaspan); however, combinations of these medications may be ordered by the Lipid MD with careful monitoring.  Use of Pravachol with Cyclosporine should also be closely monitored.

 

 

Possible side effects

 

Pravachol  is generally well tolerated; side effects usually have been mild and temporary. Call your doctor or our office if you have:  GI problems, rash, fatigue, cold/flu symptoms, muscle aches, headaches, or dizziness.  However, report muscle pain and brown urine to us immediately, particularly if accompanied by fever and/or weakness.

 

 

Lab tests

 

In addition to a lipid profile, the lab tests AST and ALT will be done periodically to help assess liver function.

 

 

Special instructions:

 

  • Always take the prescribed amount of medicine.

     

  • Avoid substantial use of alcohol.

     

  • Have lab tests done promptly when ordered to avoid risks.

     

 

PRECAUTION

 

Women capable of childbearing must have a pregnancy test (serum HCG) before starting this medication. This is a category X drug and not recommended for use during pregnancy or lactation.

 

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